Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047592 | 1.00 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9047580 | 1.00 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9047597 | 1.00 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9047586 | 1.00 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9049260 | 0.88 | CCR5 (0.37) | ALDH1A1POLBATMCCR5 | |
| SCHEMBL9049261 | 0.88 | CCR5 (0.37) | ALDH1A1POLBATMCCR5 | |
| SCHEMBL9049245 | 0.88 | CCR5 (0.37) | ALDH1A1POLBATMCCR5 | |
| SCHEMBL9049255 | 0.88 | CCR5 (0.37) | ALDH1A1POLBATMCCR5 | |
| SCHEMBL9049251 | 0.88 | CCR5 (0.37) | ALDH1A1POLBATMCCR5 | |
| SCHEMBL4458969 | 0.87 | MITF (0.39) | NPC1RAB9AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |