Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.60 |
| ▸ | DRD2 | P14416 | 6/20 | 0.59 |
| ▸ | HRH1 | P35367 | 6/20 | 0.59 |
| ▸ | DRD3 | P35462 | 6/20 | 0.59 |
| ▸ | HTR2B | P41595 | 6/20 | 0.59 |
| ▸ | HTR1A | P08908 | 5/20 | 0.59 |
| ▸ | DRD4 | P21917 | 5/20 | 0.59 |
| ▸ | HTR7 | P34969 | 5/20 | 0.59 |
| ▸ | HTR2A | P28223 | 4/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.59 |
| ▸ | HTR6 | P50406 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904910 | 0.91 | OPRM1 (0.66) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL904907 | 0.90 | OPRM1 (0.56) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL6402803 | 0.86 | OPRM1 (0.74) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL16256973 | 0.82 | OPRM1 (0.67) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL5296387 | 0.82 | OPRM1 (0.67) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL11669922 | 0.82 | OPRM1 (0.71) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL9070731 | 0.80 | OPRM1 (0.56) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL11932466 | 0.79 | OPRM1 (0.72) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| Hydrochloric Acid SCHEMBL7883474 | 0.78 | OPRM1 (0.77) | OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL904846 | 0.78 | OPRM1 (0.62) | OPRM1OPRK1OPRL1OPRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |