Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | THPO | P40225 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046003 | 0.89 | SIGMAR1 (0.66) | SIGMAR1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL9048214 | 0.83 | SIGMAR1 (0.70) | SIGMAR1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL988286 | 0.80 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL12648367 | 0.80 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL30687922 | 0.80 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL7698474 | 0.76 | SIGMAR1 (0.62) | SIGMAR1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL8119380 | 0.74 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL9047802 | 0.74 | SIGMAR1 (0.76) | SIGMAR1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL9050714 | 0.74 | SIGMAR1 (0.67) | SIGMAR1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL7094797 | 0.72 | SIGMAR1 (0.78) | SIGMAR1MEN1KMT2ACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406111-B1 | Substituted arylamines and heteroarylamines, process for their preparation and pharmaceutical composition containing them | SOD CONSEILS RECH APPLIC (FR) | 1996-10-09 | — | — | EP | claimed |