SCHEMBL988286

SCHEMBL988286

c1ccc2sc(C3(N4CCCCC4)CCCCC3)cc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 12/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
TSHR P16473 1/20 1.00
CYP2C19 P33261 1/20 1.00
THPO P40225 1/20 1.00
SLC6A3 Q01959 1/20 1.00
PMP22 Q01453 1/20 0.97
NPSR1 Q6W5P4 1/20 0.97
PRCP P42785 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12648367 1.00 SIGMAR1 (1.00) SIGMAR1MEN1KMT2ACYP3A4CYP2D6
SCHEMBL30687922 1.00 SIGMAR1 (1.00) SIGMAR1MEN1KMT2ACYP3A4CYP2D6
SCHEMBL7094797 0.88 SIGMAR1 (0.78) SIGMAR1MEN1KMT2ACYP3A4CYP2D6
SCHEMBL9047802 0.86 SIGMAR1 (0.76) SIGMAR1MEN1KMT2ACYP3A4CYP2D6
SCHEMBL9048214 0.83 SIGMAR1 (0.70) SIGMAR1MEN1KMT2ACYP3A4CYP2D6
SCHEMBL9050714 0.81 SIGMAR1 (0.67) SIGMAR1MEN1KMT2ACYP3A4CYP2D6
SCHEMBL9046003 0.80 SIGMAR1 (0.66) SIGMAR1MEN1KMT2ACYP3A4CYP2D6
SCHEMBL9049352 0.80 SIGMAR1 (0.66) SIGMAR1MEN1KMT2ACYP3A4CYP2D6
SCHEMBL7698474 0.78 SIGMAR1 (0.62) SIGMAR1MEN1KMT2ACYP3A4CYP2D6
SCHEMBL7095248 0.74 SIGMAR1 (1.00) SIGMAR1MEN1KMT2ACYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629654-B2 Concentration of chemical species through the use of photosenstive sorbent materials GENESIS SYSTEMS LLC (US) 2026-05-19 US claimed
EP-4618976-A1 COMPOSITIONS AND METHODS OF TREATING NEUROLOGICAL CONDITIONS Dri Biosciences Corporation (US) 2025-09-24 EP claimed
WO-2025129263-A1 TREATMENT OF BREAKTHROUGH CANCER PAIN InhaleRx Ltd (AU) 2025-06-26 WO claimed
CN-120192766-A BTCP-Ac@Eu-MOF double-fluorescence-emission fluorescent probe and preparation method and application thereof 南京黄教授食品科技有限公司 2025-06-24 CN claimed
US-20250197653-A1 MODULATING OBJECT SIGNATURES THROUGH THE USE OF PHOTOSENSTIVE SORBENT COATINGS GENESIS SYSTEMS LLC 2025-06-19 US claimed
US-20250196095-A1 CONCENTRATION OF CHEMICAL SPECIES THROUGH THE USE OF PHOTOSENSTIVE SORBENT MATERIALS GENESIS SYSTEMS LLC 2025-06-19 US claimed
US-20240398978-A1 Compositions and Methods for Treating Dopamine Disorders METAQOR LLC (US) 2024-12-05 US claimed
EP-3386493-B1 DBH INHIBITORS FOR TREATING OR PREVENTING MEMORY LOSS UNIV BRANDEIS (US) 2024-11-20 EP claimed
WO-2024160196-A1 USE OF BENCYCLOQUIDIUM BROMIDE, ISOMER THEREOF AND DERIVATIVE THEREOF IN PREPARATION OF OPHTHALMIC FORMULATION 北京银谷医药科技有限公司 2024-08-08 WO claimed
WO-2024107961-A1 COMPOSITIONS AND METHODS OF TREATING NEUROLOGICAL CONDITIONS DRI BIOSCIENCES CORPORATION (US) 2024-05-23 WO claimed
WO-2024074850-A1 A TREATMENT FOR MENTAL DISORDERS ReWire Therapeutics Limited (GB) 2024-04-11 WO claimed
CN-103000810-A Photodiode SAMSUNG ELECTRONICS CO LTD 2013-03-27 CN claimed
US-20260137691-A1 WB3 FOR ANESTHESIA AND TREATING PAIN PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-05-21 US disclosed
US-12629654-B2 Concentration of chemical species through the use of photosenstive sorbent materials GENESIS SYSTEMS LLC (US) 2026-05-19 US disclosed
CN-122046944-A Optimal design and thermal error suppression method for liquid cooling bionic flow channel of electric spindle of numerical control machine tool 宁波大学 2026-05-15 CN disclosed
US-12624030-B2 4-amino-3-(4-phenoxyphenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one derivatives and salts thereof PRINCIPIA BIOPHARMA INC. (US) 2026-05-12 US disclosed
WO-1997012513-A1 DOPAMINE TRANSPORTER KNOCKOUT MICE DUKE UNIVERSITY (US) 1997-04-10 WO disclosed
EP-0751937-A1 N-(BENZHYDRYLOXYALKYL)-4-(CARBOXY/CARBAMOYL-METHYL)-PIPERIDINE DERIVATIVES AS ANTIDEPRESSANTS COOPERATION PHARMACEUTIQUE FRANCAISE (FR) 1997-01-08 EP disclosed
WO-1995026336-A1 N-(BENZHYDRYLOXYALKYL)-4-(CARBOXY/CARBAMOYL-METHYL)-PIPERIDINE DERIVATIVES AS ANTIDEPRESSANTS COOPERATION PHARMACEUTIQUE FRANCAISE (FR) 1995-10-05 WO disclosed
US-5248686-A Treatment of nervous depression CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1993-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137691-A1 WB3 FOR ANESTHESIA AND TREATING PAIN WNT3, TRPV3, ADRB3 SIGMAR1 576/4885MEN1 4805/4885KMT2A 4685/4885
US-12629654-B2 Concentration of chemical species through the use of photosenstive sorbent materials TRPV4, TRPA1, TRPM4 SIGMAR1 2143/4885MEN1 2698/4885KMT2A 4756/4885
US-20240398978-A1 Compositions and Methods for Treating Dopamine Disorders SLC6A3, SNCA, CLTA SIGMAR1 182/4885MEN1 4442/4885KMT2A 1493/4885
US-12624030-B2 4-amino-3-(4-phenoxyphenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one derivatives and salts thereof ADRA1D, ADRA2C, P2RY1 SIGMAR1 126/4885MEN1 1796/4885KMT2A 2925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.