Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9048446 | 0.97 | CHRM2 (0.42) | CHRM2CHRM4CHRM1CHRM3USP2 | |
| SCHEMBL9050441 | 0.95 | CHRM2 (0.50) | CHRM2CHRM4CHRM1CHRM3USP2 | |
| Oxalic Acid SCHEMBL9051874 | 0.93 | CHRM1 (0.41) | CHRM2CHRM4CHRM1CHRM3USP2 | |
| SCHEMBL9052128 | 0.91 | CHRM2 (0.45) | CHRM2CHRM4CHRM1CHRM3USP2 | |
| Oxalic Acid SCHEMBL8791271 | 0.90 | CHRM2 (0.39) | CHRM2CHRM4CHRM1CHRM3USP2 | |
| SCHEMBL3318136 | 0.88 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3USP2 | |
| SCHEMBL8790010 | 0.84 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3USP2 | |
| Oxalic Acid SCHEMBL6625634 | 0.77 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL6629844 | 0.77 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL7435543 | 0.77 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287356-B1 | Bridgehead substituted azabicyclic derivatives | BEECHAM GROUP PLC (GB) | 1996-01-24 | — | — | EP | disclosed |
| US-5132316-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1992-07-21 | — | — | US | disclosed |
| US-4971975-A | TREATMENT OF DEMENTIA; AZABICYCLOOCTANE COMPOUNDS | BEECHAM GROUP PLC (GB) | 1990-11-20 | — | — | US | disclosed |