Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | DRD1 | P21728 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050993 | 0.90 | PTGIR (0.39) | PTGIRACHE | |
| SCHEMBL9047704 | 0.88 | DRD2 (0.37) | PTGIRDRD2DRD1DRD3CYP1A2 | |
| SCHEMBL9050737 | 0.83 | NPSR1 (0.37) | PTGIRDRD2DRD1DRD3CYP1A2 | |
| SCHEMBL9049479 | 0.82 | PTGIR (0.59) | PTGIR | |
| SCHEMBL9049474 | 0.81 | PTGIR (0.43) | PTGIRACHE | |
| SCHEMBL9049789 | 0.80 | PTGIR (0.41) | PTGIRACHEDRD2DRD1DRD3 | |
| SCHEMBL9051775 | 0.79 | PTGIR (0.40) | PTGIRACHE | |
| SCHEMBL9047644 | 0.78 | PTGIR (0.36) | PTGIRDRD2DRD1DRD3CYP1A2 | |
| SCHEMBL9046367 | 0.77 | PTGIR (0.39) | PTGIR | |
| SCHEMBL9046065 | 0.77 | DRD2 (0.38) | DRD2DRD1DRD3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |