Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051775 | 0.91 | PTGIR (0.40) | PTGIRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9048870 | 0.91 | ALDH1A1 (0.40) | PTGIRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9048366 | 0.84 | PTGIR (0.43) | PTGIRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9046372 | 0.83 | PTGIR (0.45) | PTGIR | |
| SCHEMBL8858396 | 0.83 | PTGIR (0.61) | PTGIR | |
| SCHEMBL9049412 | 0.83 | ALDH1A1 (0.39) | PTGIRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9048134 | 0.81 | PTGIR (0.45) | PTGIRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9049469 | 0.77 | PTGIR (0.38) | PTGIR | |
| SCHEMBL9049789 | 0.75 | PTGIR (0.41) | PTGIR | |
| SCHEMBL9045869 | 0.74 | LMNA (0.51) | ALDH1A1KMT2AMEN1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |