Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 15/20 | 0.66 |
| ▸ | HTR7 | P34969 | 5/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.63 |
| ▸ | MPO | P05164 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620285 | 0.91 | HTR1A (0.66) | HTR1AHTR7SLC6A4KCNH2MPO | |
| Hydrochloric Acid SCHEMBL9049018 | 0.90 | HTR1A (0.65) | HTR1AHTR7SLC6A4KCNH2MPO | |
| SCHEMBL9047985 | 0.90 | HTR1A (0.69) | HTR1A | |
| Hydrochloric Acid SCHEMBL9048598 | 0.90 | HTR1A (0.64) | HTR1AHTR7SLC6A4KCNH2MPO | |
| SCHEMBL9048166 | 0.87 | HTR1A (0.51) | HTR1AHTR7SLC6A4KCNH2MPO | |
| SCHEMBL6765833 | 0.84 | HTR1A (0.48) | HTR1AHTR7SLC6A4KCNH2 | |
| SCHEMBL4357142 | 0.84 | HTR1A (0.68) | HTR1AHTR7SLC6A4KCNH2MPO | |
| Hydrochloric Acid SCHEMBL4356376 | 0.83 | HTR1A (0.70) | HTR1AHTR7SLC6A4KCNH2MPO | |
| Hydrochloric Acid SCHEMBL4347864 | 0.83 | HTR1A (0.70) | HTR1AHTR7SLC6A4KCNH2MPO | |
| SCHEMBL6765827 | 0.83 | HTR1D (0.53) | HTR1AHTR7SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714896-A1 | INDOL DERIVATIVES USEFUL FOR THE TREATMENT OF MIGRAINE, COMPOSITION AND UTILIZATION | VITA-INVEST, S.A. (ES) | 1996-06-05 | — | — | EP | claimed |
| EP-0714896-A1 | INDOL DERIVATIVES USEFUL FOR THE TREATMENT OF MIGRAINE, COMPOSITION AND UTILIZATION | VITA-INVEST, S.A. (ES) | 1996-06-05 | — | — | EP | disclosed |