SCHEMBL9049792

SCHEMBL9049792

C=Cc1ccc(CCl)c2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
KMT2A Q03164 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
GCGR P47871 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1976914 0.82 GCGR (0.39) ALDH1A1L3MBTL1GCGRTSHR
SCHEMBL4507349 0.80 CNR2 (0.39) ALDH1A1KMT2A
SCHEMBL2100602 0.80 ALDH1A1 (0.48) ALDH1A1KMT2ATSHR
SCHEMBL2466440 0.80 L3MBTL1 (0.44) ALDH1A1KMT2AL3MBTL1TSHR
SCHEMBL29434197 0.80 ALDH1A1 (0.48) ALDH1A1KMT2ATSHR
SCHEMBL29558862 0.80 L3MBTL1 (0.44) ALDH1A1KMT2AL3MBTL1TSHR
SCHEMBL808751 0.78 ALDH1A1 (0.33) ALDH1A1
SCHEMBL2664057 0.77 TDP1 (0.34) ALDH1A1GCGRTSHR
SCHEMBL18905541 0.77 ALDH1A1 (0.32) ALDH1A1
SCHEMBL5131346 0.77 CNR2 (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5491189-A BINDER DISPERSION CONSISTS OF A HALOGENATED COPOLYMER OF 2,3-DIHALO-1,3-BUTADIENE, AROMATIC MONOALKYENE ALKYL HALIDE, UNSATURATED OLEFIN, AND CONTAINS ADDITIVE, PARTLY SAPONIFIED VINYL ACETATE COPOLYMER, AROMATIC POLYNITROSO COMPOUNDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-02-13 US disclosed
US-4483962-A TERPOLYMER OF 2,8-DIHALO-1,3-BUTADIENE, MONOALKENYL AROMATIC ALKYL HALIDE, AND UNSATURATED ACID MONOMER LORD CORPORATION (US) 1984-11-20 US disclosed
US-4086406-A HIGH MOLECULAR WEIGHT, OZONE RESISTANCE PHILLIPS PETROLEUM COMPANY (US) 1978-04-25 US disclosed
US-4074035-A ISOBUTYLENE AND PARA AND META CHLOROMETHYL STYRENE EXXON RESEARCH & ENGINEERING CO. (US) 1978-02-14 US disclosed
US-4070295-A Sulfone copolymeric additive for hydrocarbon oils EXXON RESEARCH AND ENGINEERING COMPANY (US) 1978-01-24 US disclosed
US-4048425-A ACRYLIC ESTERS, MONO-OLEFINS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-09-13 US disclosed
US-4014662-A ETHYLENE POLYMERS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-03-29 US disclosed