Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049927 | 1.00 | RXRA (0.51) | RXRARXRBRXRGPTGER3PTGER2 | |
| SCHEMBL6274122 | 0.83 | PTGER3 (0.63) | PTGER3PTGER2PTGER4MAPTHTT | |
| SCHEMBL6274118 | 0.83 | PTGER3 (0.63) | PTGER3PTGER2PTGER4MAPTHTT | |
| SCHEMBL26046363 | 0.82 | LMNA (0.59) | PTGER3PTGER2PTGER4MAPTKDM4E | |
| SCHEMBL8479091 | 0.81 | MAPT (0.62) | RXRARXRBRXRGPTGER3PTGER2 | |
| SCHEMBL8479095 | 0.81 | MAPT (0.62) | RXRARXRBRXRGPTGER3PTGER2 | |
| SCHEMBL20390172 | 0.79 | BACE1 (0.50) | RXRARXRBRXRGPTGER3PTGER2 | |
| SCHEMBL3183029 | 0.76 | MAPT (0.55) | PTGER3PTGER2PTGER4MAPTALDH1A1 | |
| SCHEMBL3183044 | 0.76 | MAPT (0.55) | PTGER3PTGER2PTGER4MAPTALDH1A1 | |
| Acetic Acid SCHEMBL11694003 | 0.75 | PDCD1 (0.38) | PTGER3PTGER2PTGER4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728742-A2 | Novel retinoids | F. HOFFMANN-LA ROCHE AG (CH) | 1996-08-28 | — | — | EP | disclosed |