SCHEMBL9050067

SCHEMBL9050067

Cn1nnn(-c2ccccc2C=NO)c1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 2/20 0.39
KDM4E B2RXH2 3/20 0.38
HTT P42858 4/20 0.35
FGF23 Q9GZV9 1/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 2/20 0.35
NFE2L2 Q16236 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
PTGS2 P35354 1/20 0.34
CA9 Q16790 1/20 0.34
HPGD P15428 4/20 0.33
LMNA P02545 4/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 1/20 0.33
USP2 O75604 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9050061 1.00 KCNN4 (0.39) KCNN4KDM4EHTTFGF23TSHR
SCHEMBL9051471 0.81 MEN1 (0.39) KCNN4KDM4EHTTTSHRALDH1A1
SCHEMBL23678421 0.79 CACNA1B (0.36) KDM4EHTTTSHRALDH1A1NFE2L2
SCHEMBL9052646 0.71 GSK3A (0.46) TSHRNFE2L2GSK3AGSK3B
SCHEMBL7750762 0.71 MGLL (0.43) KCNN4KDM4EALDH1A1MAPT
SCHEMBL7750768 0.71 MGLL (0.43) KCNN4KDM4EALDH1A1MAPT
SCHEMBL9051455 0.71 KCNN4 (0.36) KCNN4TSHRALDH1A1NFE2L2HPGD
SCHEMBL24199549 0.68 ALDH1A1 (0.31) ALDH1A1
SCHEMBL24199500 0.68
SCHEMBL24199550 0.68 MEN1 (0.33) ALDH1A1NFE2L2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996036229-A1 FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-11-21 WO disclosed