Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 4/20 | 0.43 |
| ▸ | GART | P22102 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050162 | 1.00 | L3MBTL1 (0.45) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9049343 | 0.97 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9049346 | 0.97 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9215363 | 0.91 | L3MBTL1 (0.45) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9535440 | 0.89 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9535434 | 0.89 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9208126 | 0.88 | DHFR (0.41) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9208063 | 0.88 | DHFR (0.42) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9446029 | 0.88 | DHFR (0.53) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9446027 | 0.88 | DHFR (0.53) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314280-B1 | Process for the preparation of fused pyridine compounds | UNIV PRINCETON (US) | 1996-02-21 | — | — | EP | disclosed |
| US-5473071-A | Process for the preparation of fused pyridine compounds | TRUSTEES OF PRINCETON UNIVERSITY (US) | 1995-12-05 | — | — | US | disclosed |
| US-4895946-A | Process for the preparation of fused pyridine compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-01-23 | — | — | US | disclosed |