Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 1.00 |
| ▸ | DRD2 | P14416 | 11/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 9/20 | 1.00 |
| ▸ | DRD3 | P35462 | 9/20 | 1.00 |
| ▸ | HTR1A | P08908 | 8/20 | 1.00 |
| ▸ | DRD4 | P21917 | 8/20 | 1.00 |
| ▸ | HTR2A | P28223 | 8/20 | 1.00 |
| ▸ | HTR2C | P28335 | 8/20 | 1.00 |
| ▸ | HTR7 | P34969 | 8/20 | 1.00 |
| ▸ | HTR1D | P28221 | 7/20 | 1.00 |
| ▸ | HTR2B | P41595 | 7/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 7/20 | 1.00 |
| ▸ | HRH2 | P25021 | 6/20 | 1.00 |
| ▸ | DRD1 | P21728 | 6/20 | 1.00 |
| ▸ | DRD5 | P21918 | 6/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 6/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 6/20 | 1.00 |
| ▸ | HTR6 | P50406 | 6/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 1.00 |
| ▸ | HTR5A | P47898 | 4/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Penfluridol SCHEMBL93939 | 0.97 | OPRM1 (1.00) | OPRM1DRD2OPRK1DRD3HTR1A | |
| Penfluridol SCHEMBL30546621 | 0.97 | OPRM1 (1.00) | OPRM1DRD2OPRK1DRD3HTR1A | |
| Penfluridol SCHEMBL28123335 | 0.94 | OPRM1 (0.94) | OPRM1DRD2OPRK1DRD3HTR1A | |
| SCHEMBL904950 | 0.93 | OPRM1 (0.89) | OPRM1DRD2OPRK1DRD3HTR1A | |
| SCHEMBL905043 | 0.90 | OPRM1 (0.87) | OPRM1DRD2OPRK1DRD3HTR1A | |
| SCHEMBL905046 | 0.89 | OPRM1 (0.85) | OPRM1DRD2OPRK1DRD3HTR1A | |
| SCHEMBL905028 | 0.89 | OPRM1 (1.00) | OPRM1DRD2OPRK1DRD3HTR1A | |
| SCHEMBL904992 | 0.88 | OPRM1 (0.84) | OPRM1DRD2OPRK1DRD3HTR1A | |
| SCHEMBL905031 | 0.87 | OPRM1 (0.81) | OPRM1DRD2OPRK1DRD3HTR1A | |
| SCHEMBL905064 | 0.87 | OPRM1 (0.84) | OPRM1DRD2OPRK1DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |