Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.61 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048216 | 0.91 | PTGIR (0.71) | PTGIRTBXAS1 | |
| SCHEMBL9048575 | 0.86 | PTGIR (0.64) | PTGIRTBXAS1 | |
| SCHEMBL9045328 | 0.86 | PTGIR (0.64) | PTGIRTBXAS1MEN1KMT2A | |
| SCHEMBL9048350 | 0.86 | PTGIR (0.69) | PTGIRTBXAS1 | |
| SCHEMBL9047528 | 0.85 | PTGIR (0.62) | PTGIRTBXAS1ALDH1A1MEN1KMT2A | |
| SCHEMBL9046463 | 0.84 | PTGIR (0.62) | PTGIRTBXAS1 | |
| SCHEMBL9568025 | 0.82 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8858482 | 0.82 | PTGIR (0.61) | PTGIRTBXAS1 | |
| SCHEMBL9050622 | 0.82 | PTGIR (0.62) | PTGIRTBXAS1 | |
| SCHEMBL9048590 | 0.81 | PTGIR (0.71) | PTGIRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |