Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.49 |
| ▸ | RARA | P10276 | 8/20 | 0.49 |
| ▸ | RARG | P13631 | 6/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | HNF4A | P41235 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049309 | 0.89 | RARB (0.52) | RARBRARARARGPDK2PDGFRB | |
| SCHEMBL9051247 | 0.88 | RARA (0.53) | RARBRARARARGPDK2PDGFRB | |
| SCHEMBL9048887 | 0.86 | RARB (0.60) | RARBRARARARGRXRA | |
| SCHEMBL9050117 | 0.85 | RARB (0.51) | RARBRARARARGPDK2PDGFRB | |
| SCHEMBL9117300 | 0.85 | RARB (0.54) | RARBRARARARGPDK2PDGFRB | |
| SCHEMBL9051118 | 0.85 | RARA (0.51) | RARBRARARARGPDK2RXRA | |
| SCHEMBL9119758 | 0.84 | RARB (0.53) | RARBRARARARGPDK2PDGFRB | |
| SCHEMBL9051778 | 0.84 | RARB (0.53) | RARBRARARARGPDK2PDGFRB | |
| SCHEMBL9050464 | 0.83 | KCNH2 (0.48) | RARBRARARARGPDK2KDM4E | |
| SCHEMBL9051144 | 0.83 | RARB (0.53) | RARBRARARARGPDK2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033745-A9 | NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY | — | 1996-01-18 | — | — | WO | disclosed |