Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 5/20 | 0.47 |
| ▸ | RARB | P10826 | 5/20 | 0.47 |
| ▸ | RARG | P13631 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9050569 | 0.86 | RARB (0.56) | RARARARBRARG | |
| SCHEMBL9049309 | 0.86 | RARB (0.52) | RARARARBRARGALDH1A1MAPT | |
| SCHEMBL9051247 | 0.85 | RARA (0.53) | RARARARBRARGPDK2 | |
| SCHEMBL9050339 | 0.83 | RARB (0.49) | KCNH2HRH3RARARARBRARG | |
| SCHEMBL9117300 | 0.82 | RARB (0.54) | RARARARBRARGESR1ESR2 | |
| SCHEMBL9051118 | 0.82 | RARA (0.51) | RARARARBRARGMAPTPDK2 | |
| SCHEMBL9119758 | 0.81 | RARB (0.53) | KCNH2HRH3RARARARBRARG | |
| SCHEMBL9051778 | 0.81 | RARB (0.53) | RARARARBRARGESR1ESR2 | |
| SCHEMBL9051144 | 0.81 | RARB (0.53) | RARARARBRARGPDK2MAPK1 | |
| SCHEMBL9050623 | 0.80 | RARB (0.52) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033745-A9 | NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY | — | 1996-01-18 | — | — | WO | disclosed |
| WO-1995033745-A2 | NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY | SRI INTERNATIONAL (US) | 1995-12-14 | — | — | WO | disclosed |