Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 9/20 | 0.39 |
| ▸ | EDNRA | P25101 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL9050394 | 0.89 | EDNRB (0.33) | EDNRBEDNRA | |
| SCHEMBL9054345 | 0.88 | EDNRB (0.42) | EDNRBEDNRA | |
| SCHEMBL9051577 | 0.86 | EDNRB (0.40) | EDNRBEDNRAKDM4ELMNA | |
| SCHEMBL9051237 | 0.86 | ALDH1A1 (0.33) | EDNRBEDNRA | |
| SCHEMBL9051600 | 0.85 | EDNRB (0.40) | EDNRBEDNRAKDM4ELMNA | |
| SCHEMBL9052951 | 0.85 | EDNRB (0.39) | EDNRBEDNRAKDM4ELMNA | |
| SCHEMBL9588704 | 0.83 | EDNRB (0.41) | EDNRBEDNRAKDM4E | |
| SCHEMBL9050413 | 0.80 | CYP24A1 (0.31) | — | |
| SCHEMBL8943529 | 0.77 | EDNRB (0.37) | EDNRBEDNRAKDM4E | |
| SCHEMBL8098308 | 0.76 | EDNRB (0.50) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996000219-A1 | PYRIMIDINYL- AND TRIAZINYL-OXY AND THIO-3-HALOALKYL-PROPIONIC ACID DERIVATIVES AS HERBICIDES | CIBA-GEIGY AG (CH) | 1996-01-04 | — | — | WO | claimed |
| WO-1996000219-A1 | PYRIMIDINYL- AND TRIAZINYL-OXY AND THIO-3-HALOALKYL-PROPIONIC ACID DERIVATIVES AS HERBICIDES | CIBA-GEIGY AG (CH) | 1996-01-04 | — | — | WO | disclosed |