SCHEMBL9051577

SCHEMBL9051577

COc1cc(OC)nc(SC(C(=O)O)C(O)(C(F)(F)F)C(F)(F)F)n1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 6/20 0.40
EDNRA P25101 6/20 0.40
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9051600 0.90 EDNRB (0.40) EDNRBEDNRAKDM4ELMNAALDH1A1
SCHEMBL9050654 0.86 EDNRB (0.39) EDNRBEDNRAKDM4ELMNA
SCHEMBL9052951 0.85 EDNRB (0.39) EDNRBEDNRAKDM4ELMNA
SCHEMBL9588704 0.83 EDNRB (0.41) EDNRBEDNRAKDM4EALDH1A1
SCHEMBL9054345 0.82 EDNRB (0.42) EDNRBEDNRAALDH1A1
SCHEMBL8943529 0.80 EDNRB (0.37) EDNRBEDNRAKDM4EALDH1A1
SCHEMBL9052337 0.79 ALDH1A1 (0.33) EDNRBEDNRAKDM4EALDH1A1
SCHEMBL8098308 0.78 EDNRB (0.50) EDNRBEDNRA
Imidazole SCHEMBL9050394 0.77 EDNRB (0.33) EDNRBEDNRA
SCHEMBL9408621 0.76 ALOX5 (0.46) EDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996000219-A1 PYRIMIDINYL- AND TRIAZINYL-OXY AND THIO-3-HALOALKYL-PROPIONIC ACID DERIVATIVES AS HERBICIDES CIBA-GEIGY AG (CH) 1996-01-04 WO claimed