Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048944 | 1.00 | HPGD (0.42) | HPGDGAAALDH1A1RAB9AFFAR1 | |
| SCHEMBL9050815 | 1.00 | HPGD (0.42) | HPGDGAAALDH1A1RAB9AFFAR1 | |
| SCHEMBL9050826 | 1.00 | HPGD (0.42) | HPGDGAAALDH1A1RAB9AFFAR1 | |
| SCHEMBL9050821 | 1.00 | HPGD (0.42) | HPGDGAAALDH1A1RAB9AFFAR1 | |
| SCHEMBL9048560 | 0.88 | ALDH1A1 (0.41) | HPGDGAAALDH1A1RAB9AFFAR1 | |
| SCHEMBL9048542 | 0.88 | ALDH1A1 (0.41) | HPGDGAAALDH1A1RAB9AFFAR1 | |
| SCHEMBL9048555 | 0.88 | ALDH1A1 (0.41) | HPGDGAAALDH1A1RAB9AFFAR1 | |
| SCHEMBL9048549 | 0.88 | ALDH1A1 (0.41) | HPGDGAAALDH1A1RAB9AFFAR1 | |
| SCHEMBL9048540 | 0.88 | ALDH1A1 (0.41) | HPGDGAAALDH1A1RAB9AFFAR1 | |
| SCHEMBL9045983 | 0.87 | ALDH1A1 (0.40) | HPGDALDH1A1RAB9AFFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | claimed |