Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048549 | 1.00 | ALDH1A1 (0.41) | ALDH1A1RAB9AHPGDMAPTTHRB | |
| SCHEMBL9048555 | 1.00 | ALDH1A1 (0.41) | ALDH1A1RAB9AHPGDMAPTTHRB | |
| SCHEMBL9048560 | 1.00 | ALDH1A1 (0.41) | ALDH1A1RAB9AHPGDMAPTTHRB | |
| SCHEMBL9048542 | 1.00 | ALDH1A1 (0.41) | ALDH1A1RAB9AHPGDMAPTTHRB | |
| SCHEMBL9050821 | 0.88 | HPGD (0.42) | ALDH1A1RAB9AHPGDMAPTKMT2A | |
| SCHEMBL9048944 | 0.88 | HPGD (0.42) | ALDH1A1RAB9AHPGDMAPTKMT2A | |
| SCHEMBL9050815 | 0.88 | HPGD (0.42) | ALDH1A1RAB9AHPGDMAPTKMT2A | |
| SCHEMBL9050824 | 0.88 | HPGD (0.42) | ALDH1A1RAB9AHPGDMAPTKMT2A | |
| SCHEMBL9050826 | 0.88 | HPGD (0.42) | ALDH1A1RAB9AHPGDMAPTKMT2A | |
| SCHEMBL4466176 | 0.87 | ALDH1A1 (0.36) | ALDH1A1RAB9AHPGDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |