SCHEMBL9050869

SCHEMBL9050869

O=C(CO)Oc1cccc2c1CCCC2CCCO

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 6/20 0.53
SIGMAR1 Q99720 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8414247 0.90 PTGIR (0.51) PTGIRSIGMAR1
SCHEMBL9050860 0.88 PTGIR (0.45) PTGIRSIGMAR1
SCHEMBL8808628 0.88 PTGIR (0.50) PTGIRSIGMAR1
SCHEMBL9050358 0.86 PTGIR (0.43) PTGIR
SCHEMBL9050863 0.85 PTGIR (0.50) PTGIRSIGMAR1
SCHEMBL9048346 0.82 PTGIR (0.52) PTGIRSIGMAR1
SCHEMBL8411211 0.82 PTGIR (0.47) PTGIRSIGMAR1
SCHEMBL8013611 0.82 SIGMAR1 (0.64) SIGMAR1
SCHEMBL8858587 0.81 PTGIR (0.72) PTGIRSIGMAR1
SCHEMBL9048486 0.81 PTGIR (0.55) PTGIRSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542203-B1 Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists ONO PHARMACEUTICAL CO (JP) 1996-07-03 EP disclosed
US-5344836-A Fused benzeneoxyacetic acid derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1994-09-06 US disclosed