Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050869 | 0.88 | PTGIR (0.53) | PTGIRSIGMAR1 | |
| SCHEMBL9050857 | 0.84 | PTGIR (0.43) | PTGIRKDM4CSIGMAR1ACHE | |
| SCHEMBL9050358 | 0.84 | PTGIR (0.43) | PTGIRACHE | |
| SCHEMBL9047496 | 0.82 | TAS1R3 (0.40) | PTGIRACHE | |
| SCHEMBL8411211 | 0.81 | PTGIR (0.47) | PTGIRSIGMAR1 | |
| SCHEMBL8019430 | 0.80 | SIGMAR1 (0.57) | SIGMAR1 | |
| SCHEMBL8811492 | 0.80 | SIGMAR1 (0.57) | SIGMAR1 | |
| SCHEMBL9050868 | 0.80 | PTGIR (0.64) | PTGIRKDM4C | |
| SCHEMBL9427328 | 0.80 | SIGMAR1 (0.44) | PTGIRKDM4CSIGMAR1ACHE | |
| SCHEMBL9048486 | 0.80 | PTGIR (0.55) | PTGIRKDM4CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |