SCHEMBL9051242

SCHEMBL9051242

O=C1c2ccccc2C(=O)c2c1ccc(O)c2C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.62
KMT2A Q03164 8/20 0.62
MEN1 O00255 7/20 0.62
ALDH1A1 P00352 7/20 0.62
MCL1 Q07820 6/20 0.62
MAPK1 P28482 4/20 0.62
BCL2 P10415 4/20 0.62
MAOA P21397 3/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
RECQL P46063 2/20 0.62
KDM4E B2RXH2 2/20 0.62
HPGD P15428 2/20 0.62
CYP3A4 P08684 1/20 0.62
ALOX15 P16050 1/20 0.62
ALOX12 P18054 1/20 0.62
APEX1 P27695 1/20 0.62
DAPK1 P53355 1/20 0.62
CYP1B1 Q16678 1/20 0.62
HSD17B10 Q99714 1/20 0.62
L3MBTL1 Q9Y468 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31214586 0.85 TTR (0.66) MAPTKMT2AMEN1ALDH1A1MCL1
SCHEMBL68628 0.82 MAPT (0.68) MAPTKMT2AMEN1ALDH1A1MCL1
SCHEMBL8757798 0.81 ELANE (0.62) MAPTKMT2AMEN1ALDH1A1MCL1
SCHEMBL9462340 0.81 KMT2A (0.61) MAPTKMT2AMEN1ALDH1A1MCL1
SCHEMBL11222823 0.81 TTR (0.55) MAPTKMT2AMEN1ALDH1A1MCL1
SCHEMBL3955176 0.79 BCL2 (0.67) MAPTKMT2AMEN1ALDH1A1MCL1
SCHEMBL9705640 0.78 ALDH1A1 (0.51) MAPTKMT2AMEN1ALDH1A1MCL1
Athraquinones A SCHEMBL4972786 0.77 MAPT (1.00) MAPTKMT2AMEN1ALDH1A1MCL1
Athraquinones A SCHEMBL21114402 0.77 MAPT (1.00) MAPTKMT2AMEN1ALDH1A1MCL1
Athraquinones A SCHEMBL18614 0.77 MAPT (1.00) MAPTKMT2AMEN1ALDH1A1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121423040-A Preparation and application of nano-enzyme 皖南医学院 2026-01-30 CN disclosed
EP-0537313-B1 ARYLALKYL ESTERS OF 4,5-DIHYDROXY-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENECARBOXYLIC ACID HAVING THERAPEUTICAL ACTIVITY GENTILI IST SPA (IT) 1996-01-17 EP disclosed