Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 4/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.67 |
| ▸ | TTR | P02766 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29407198 | 0.87 | BCL2 (0.67) | BCL2MCL1TTRALDH1A1MEN1 | |
| SCHEMBL6548219 | 0.87 | BCL2 (0.67) | BCL2MCL1TTRALDH1A1MEN1 | |
| SCHEMBL29388375 | 0.80 | BCL2 (1.00) | BCL2MCL1TTRALDH1A1MEN1 | |
| SCHEMBL555230 | 0.80 | BCL2 (1.00) | BCL2MCL1TTRALDH1A1MEN1 | |
| SCHEMBL29384381 | 0.80 | BCL2 (1.00) | BCL2MCL1TTRALDH1A1MEN1 | |
| SCHEMBL9051242 | 0.79 | MAPT (0.62) | BCL2MCL1TTRALDH1A1MEN1 | |
| SCHEMBL9131211 | 0.79 | ALDH1A1 (0.52) | BCL2MCL1TTRALDH1A1MEN1 | |
| SCHEMBL28019688 | 0.78 | MAPT (0.55) | BCL2MCL1TTRALDH1A1MEN1 | |
| SCHEMBL3174840 | 0.76 | BCL2 (0.71) | BCL2MCL1TTRALDH1A1MEN1 | |
| SCHEMBL29178228 | 0.76 | MCL1 (0.71) | BCL2MCL1TTRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945269-A | Rhein carboxylic acid esters derivative and appliance | CHANGZHOU SHANMEI PHARMACEUTICAL RES & DEV CT CO LTD | 2015-09-30 | — | — | CN | disclosed |
| CN-104926754-A | Rhein derivant and application thereof | CHANGZHOU SHANMEI PHARMACEUTICAL RES & DEV CT CO LTD | 2015-09-23 | — | — | CN | disclosed |
| CN-101573321-A | Salts of dihydroxyanthraquinone carboxylic acids and their therapeutic use | SOSEI R & D LTD (GB) | 2009-11-04 | — | — | CN | disclosed |
| CN-101573321-A | Salts of dihydroxyanthraquinone carboxylic acids and their therapeutic use | SOSEI R & D LTD (GB) | 2009-11-04 | — | — | CN | disclosed |
| US-20090270494-A1 | Salts of Dihydroxyanthraquinone Carboxylic Acids and Their Therapeutic Use | SOSEI R&D LTD. (GB) | 2009-10-29 | — | — | US | disclosed |
| EP-2079676-A1 | SALTS OF DIHYDROXYANTHRAQUINONE CARBOXYLIC ACIDS AND THEIR THERAPEUTIC USE | Sosei R&D Ltd. (GB) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008056156-A1 | SALTS OF DIHYDROXYANTHRAQUINONE CARBOXYLIC ACIDS AND THEIR THERAPEUTIC USE | SOSEI R & D LTD. (GB) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270494-A1 | Salts of Dihydroxyanthraquinone Carboxylic Acids and Their Therapeutic Use | NR0B1, NR5A2, NR5A1 | BCL2 4007/4885MCL1 3861/4885TTR 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.