Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13024368 | 0.88 | TNIK (0.47) | ALDH1A1KMT2AMITFTP53NPC1 | |
| SCHEMBL18279956 | 0.83 | KMT2A (0.43) | ALDH1A1KMT2AMITFTP53NPC1 | |
| SCHEMBL20414933 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KMT2AMITFTP53NPC1 | |
| SCHEMBL5352040 | 0.83 | SMN1; SMN2 (0.56) | ALDH1A1KMT2AMITFTP53NPC1 | |
| SCHEMBL6331111 | 0.81 | AXL (0.54) | KMT2ANPC1RAB9AMEN1GCGR | |
| SCHEMBL3472227 | 0.79 | MEN1 (0.56) | ALDH1A1KMT2ATP53NPC1RAB9A | |
| SCHEMBL18216836 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KMT2AMITFTP53NPC1 | |
| SCHEMBL22353107 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KMT2AMITFTP53NPC1 | |
| SCHEMBL14624000 | 0.79 | RAB9A (0.55) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL13024370 | 0.79 | MAPT (0.61) | ALDH1A1KMT2ATP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731795-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-09-18 | — | — | EP | disclosed |