Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050429 | 0.92 | HCRTR1 (0.32) | HCRTR1HCRTR2 | |
| Oxalic Acid SCHEMBL9051385 | 0.79 | HSD11B1 (0.39) | HCRTR1HCRTR2DPP4 | |
| Oxalic Acid SCHEMBL9050512 | 0.76 | HSD11B1 (0.41) | DPP4 | |
| Oxalic Acid SCHEMBL9703375 | 0.75 | PDK2 (0.35) | — | |
| Oxalic Acid SCHEMBL8790622 | 0.73 | HSD11B1 (0.41) | DPP4 | |
| Oxalic Acid SCHEMBL9050722 | 0.72 | CHRM2 (0.42) | — | |
| Oxalic Acid SCHEMBL9586279 | 0.72 | — | — | |
| Oxalic Acid SCHEMBL9879691 | 0.71 | — | — | |
| Oxalic Acid SCHEMBL9049301 | 0.69 | ACE2 (0.30) | — | |
| SCHEMBL1482842 | 0.69 | HCRTR1 (0.36) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287356-B1 | Bridgehead substituted azabicyclic derivatives | BEECHAM GROUP PLC (GB) | 1996-01-24 | — | — | EP | disclosed |
| US-5132316-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1992-07-21 | — | — | US | disclosed |
| EP-0287356-A2 | Bridgehead substituted azabicyclic derivatives | BEECHAM GROUP PLC (GB) | 1988-10-19 | — | — | EP | disclosed |