Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790483 | 0.93 | BCHE (0.52) | BCHEACHEMAPTPOLBPKM | |
| SCHEMBL9051926 | 0.91 | BCHE (0.50) | BCHEACHEMAPTPOLBPKM | |
| SCHEMBL9051205 | 0.89 | BCHE (0.49) | BCHEACHEMAPTPOLBPKM | |
| SCHEMBL8107611 | 0.89 | MAPT (0.60) | BCHEACHEMAPTPOLBPKM | |
| SCHEMBL8147273 | 0.85 | MAPT (0.65) | MAPTPOLBPKMKDM4EALDH1A1 | |
| SCHEMBL9052218 | 0.85 | MAPT (0.51) | BCHEACHEMAPTPOLBPKM | |
| SCHEMBL9049943 | 0.83 | MAPT (0.52) | BCHEACHEMAPTPOLBPKM | |
| SCHEMBL6746867 | 0.83 | ALDH1A1 (0.53) | BCHEACHEMAPTPOLBPKM | |
| SCHEMBL13043461 | 0.83 | KAT2B (0.49) | MAPTPOLBPKMALDH1A1KMT2A | |
| SCHEMBL10804680 | 0.83 | ALDH1A1 (0.66) | MAPTPOLBPKMALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444158-B1 | CONJUGATED POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | UNIV CALIFORNIA (US) | 1996-01-03 | — | — | EP | disclosed |
| EP-0368562-B1 | Determination of the functionalization of a solid support | MERCK & CO INC (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5314817-A | Hapten modified with pyrimidine dimer or benzylammonium group, useful in reactions of proteins, nucleic acids and carbohydrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-05-24 | — | — | US | disclosed |
| US-5302516-A | Polypeptides having a binding site specific for a reactant and having an active functionality near that site to promote or catalyze the reaction; kinetics | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-04-12 | — | — | US | disclosed |
| US-5215889-A | CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-06-01 | — | — | US | disclosed |
| US-5162218-A | Conjugated polypeptides and methods for their preparation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0444158-A4 | CONJUGATED POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | — | 1992-06-24 | — | — | EP | disclosed |
| EP-0445214-A4 | CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | — | 1991-11-13 | — | — | EP | disclosed |
| EP-0445214-A1 | CATALYTIC AND REACTIVE ANTIBODIES AND ANTIBODY FRAGMENTS AND METHODS FOR THEIR PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-11 | — | — | EP | disclosed |
| EP-0444158-A1 | CONJUGATED POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE. | UNIV CALIFORNIA (US) | 1991-09-04 | — | — | EP | disclosed |
| US-4988625-A | CARBONYLDIIMIDAZOLE TREATMENT OF THE SUPPORT CROSSLINKING TO FORM A CARBAMATE WITH POLYSACCHARIDES | MERCK & CO., INC. (US) | 1991-01-29 | — | — | US | disclosed |
| WO-1990005746-A1 | CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-05-31 | — | — | WO | disclosed |
| WO-1990005749-A1 | CONJUGATED POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-05-31 | — | — | WO | disclosed |
| EP-0368562-A2 | Determination of the functionalization of a solid support | MERCK & CO. INC. (US) | 1990-05-16 | — | — | EP | disclosed |