Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147273 | 0.93 | MAPT (0.65) | MAPTPOLBPKMKDM4EALDH1A1 | |
| SCHEMBL9663877 | 0.92 | MAPT (0.56) | MAPTPOLBPKMKDM4EALDH1A1 | |
| SCHEMBL10622798 | 0.91 | KAT2B (0.72) | MAPTPOLBPKMKDM4EALDH1A1 | |
| SCHEMBL6745448 | 0.90 | MAPT (0.59) | MAPTPOLBPKMKDM4EALDH1A1 | |
| SCHEMBL14063303 | 0.90 | HCAR3 (0.65) | MAPTPOLBPKMKDM4EALDH1A1 | |
| SCHEMBL29375013 | 0.90 | KAT2B (0.58) | MAPTPOLBPKMKDM4EALDH1A1 | |
| SCHEMBL502704 | 0.90 | KAT2B (0.58) | MAPTPOLBPKMKDM4EALDH1A1 | |
| SCHEMBL563763 | 0.90 | PKM (0.67) | MAPTPOLBPKMKDM4EALDH1A1 | |
| SCHEMBL891444 | 0.90 | MAPT (0.55) | MAPTPOLBPKMKDM4EALDH1A1 | |
| SCHEMBL2228520 | 0.89 | KAT2B (0.66) | MAPTPOLBPKMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6024768-A | HUMAN HAIR COLORING; HAIR CONDITIONERS | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 2000-02-15 | — | — | US | disclosed |
| EP-0970041-A1 | NEW DIAMINOALKANE AND OXIDATION DYEING AGENT | Hans Schwarzkopf GmbH & Co. KG (DE) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998001418-A1 | NEW DIAMINOALKANE AND OXIDATION DYEING AGENT | HANS SCHWARZKOPF GMBH & CO.KG (DE) | 1998-01-15 | — | — | WO | disclosed |