Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 14/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14703260 | 0.81 | HPGD (0.57) | HPGDALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL21163104 | 0.75 | HPGD (0.62) | HPGDALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL16466885 | 0.73 | HPGD (0.55) | HPGDALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL20594175 | 0.73 | L3MBTL1 (0.61) | HPGDALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL31536222 | 0.72 | HPGD (0.59) | HPGDALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL4159647 | 0.72 | LMNA (0.61) | HPGDALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL24016897 | 0.70 | HPGD (0.56) | HPGDALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL18856526 | 0.70 | KDM4E (0.59) | HPGDALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL14703236 | 0.70 | HPGD (0.50) | HPGDALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL22059676 | 0.69 | HPGD (0.51) | HPGDALDH1A1KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996041802-A1 | NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-12-27 | — | — | WO | disclosed |