SCHEMBL9051985

SCHEMBL9051985

CCCC[Si](C)(C)OS(=O)(=O)CC(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.31
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2058043 0.81 CA1 (0.32)
SCHEMBL425715 0.78 EPHX1 (0.35) EPHX1
SCHEMBL2057929 0.77 FAAH (0.31)
SCHEMBL14779549 0.74 CA1 (0.30)
SCHEMBL1059931 0.74 CA1 (0.30)
SCHEMBL9051981 0.74
SCHEMBL2058032 0.73 CA2 (0.36)
SCHEMBL2057720 0.72 CA1 (0.32)
SCHEMBL17466440 0.72 FAAH (0.43) CES1EPHX1
SCHEMBL5960735 0.71 EPHX1 (0.41) CES1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996001811-A1 2-SUBSTITUTED 1,25-DIHYDROXYVITAMIN D3 DERIVATIVES THE JOHNS-HOPKINS UNIVERSITY (US) 1996-01-25 WO disclosed