SCHEMBL9052176

SCHEMBL9052176

CCCC(N)(Sc1ccccc1)C(=O)OCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
L3MBTL1 Q9Y468 3/20 0.42
MAPK1 P28482 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
KMT2A Q03164 2/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
LMNA P02545 2/20 0.39
MEN1 O00255 1/20 0.39
HCAR2 Q8TDS4 1/20 0.38
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4622404 0.81 ALDH1A1 (0.51) ALDH1A1L3MBTL1MAPK1TDP1CYP3A4
SCHEMBL27859704 0.80 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPK1TDP1CYP3A4
SCHEMBL27859835 0.80 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPK1TDP1CYP3A4
Hydrochloric Acid SCHEMBL10636148 0.80 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPK1TDP1CYP3A4
SCHEMBL7440964 0.78 ALDH1A1 (0.49) ALDH1A1L3MBTL1MAPK1TDP1CYP3A4
SCHEMBL28366123 0.78 ALDH1A1 (0.49) ALDH1A1L3MBTL1MAPK1TDP1CYP3A4
SCHEMBL28362146 0.78 ALDH1A1 (0.49) ALDH1A1L3MBTL1MAPK1TDP1CYP3A4
SCHEMBL28004291 0.77 ALDH1A1 (0.55) ALDH1A1L3MBTL1MAPK1TDP1CYP3A4
SCHEMBL6393090 0.76 ALDH1A1 (0.53) ALDH1A1L3MBTL1MAPK1TDP1CYP3A4
SCHEMBL11640091 0.76 ALDH1A1 (0.53) ALDH1A1L3MBTL1MAPK1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722439-A1 HIV PROTEASE INHIBITORS AGOURON PHARMACEUTICALS, INC. (US) 1996-07-24 EP disclosed