Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440964 | 1.00 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HIF1ATDP1MAPK1 | |
| SCHEMBL28362146 | 1.00 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HIF1ATDP1MAPK1 | |
| SCHEMBL149592 | 0.91 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HIF1ATDP1MAPK1 | |
| SCHEMBL8674203 | 0.89 | CETP (0.48) | ALDH1A1SMN1; SMN2HIF1ATDP1MAPK1 | |
| SCHEMBL2963546 | 0.89 | CETP (0.48) | ALDH1A1SMN1; SMN2HIF1ATDP1MAPK1 | |
| SCHEMBL8643594 | 0.88 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HIF1ATDP1MAPK1 | |
| SCHEMBL7476437 | 0.88 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HIF1ATDP1MAPK1 | |
| SCHEMBL4550673 | 0.88 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HIF1ATDP1MAPK1 | |
| SCHEMBL27486548 | 0.86 | GRM2 (0.43) | ALDH1A1SMN1; SMN2HIF1ATDP1MAPK1 | |
| Hydrochloric Acid SCHEMBL11265034 | 0.86 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HIF1ATDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869375-B | 2-oxo-1-imidazolidinylimidazothiadiazole derivatives | UCB生物制药有限责任公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-110869375-A | 2-oxo-1-imidazolidinylimidazothiadiazole derivatives | UCB生物制药有限责任公司 | 2020-03-06 | — | — | CN | disclosed |