Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418873 | 0.81 | MAP3K14 (0.38) | GLAMAP3K14CRBNCYP19A1DDB1 | |
| SCHEMBL5570558 | 0.81 | MAP3K14 (0.38) | GLAMAP3K14CRBNCYP19A1DDB1 | |
| SCHEMBL29956517 | 0.78 | MAP3K14 (0.41) | GLAMAP3K14CRBNNPC1CYP19A1 | |
| SCHEMBL11605802 | 0.76 | ALDH1A1 (0.55) | NPC1LMNAMAPT | |
| SCHEMBL11604473 | 0.76 | GLA (0.40) | GLAMAP3K14 | |
| SCHEMBL288567 | 0.76 | ALDH1A1 (0.44) | GLAMAP3K14CRBNCYP19A1LMNA | |
| SCHEMBL11605432 | 0.75 | ALDH1A1 (0.57) | NPC1CYP19A1LMNAMAPT | |
| SCHEMBL10772583 | 0.75 | ALDH1A1 (0.57) | NPC1CYP19A1LMNAMAPT | |
| SCHEMBL11605605 | 0.75 | ALDH1A1 (0.57) | NPC1CYP19A1LMNAMAPT | |
| SCHEMBL29044524 | 0.74 | ALDH1A1 (0.42) | GLAMAP3K14CRBNCYP19A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731802-A1 | N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES AS NEUROLEPTIKA ASF | BASF AKTIENGESELLSCHAFT (DE) | 1996-09-18 | — | — | EP | disclosed |
| WO-1995015327-A1 | N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES AS NEUROLEPTIKA ASF | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-08 | — | — | WO | disclosed |