Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288567 | 0.81 | ALDH1A1 (0.44) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL4351656 | 0.81 | MAP3K14 (0.40) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL29044524 | 0.79 | ALDH1A1 (0.42) | MAP3K14GLACRBNDDB1FFAR1 | |
| Ammonia Solution, Strong SCHEMBL27683456 | 0.79 | ALDH1A1 (0.42) | MAP3K14GLACRBNDDB1FFAR1 | |
| Methane SCHEMBL27514434 | 0.79 | ALDH1A1 (0.42) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL28479332 | 0.79 | MAP3K14 (0.50) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL5570558 | 0.78 | MAP3K14 (0.38) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL4418873 | 0.78 | MAP3K14 (0.38) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL9052247 | 0.78 | GLA (0.39) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL17907172 | 0.77 | MAP3K14 (0.48) | MAP3K14GLACRBNDDB1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |