Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301980 | 0.91 | MMP8 (0.54) | KMT2AMMP8SMN1; SMN2PIN1MEN1 | |
| SCHEMBL4534323 | 0.83 | CYP1A2 (0.53) | MMP8LMNASMN1; SMN2HTTPIN1 | |
| SCHEMBL5728738 | 0.82 | KMT2A (0.64) | KMT2AMMP8SMN1; SMN2PIN1MEN1 | |
| SCHEMBL1645937 | 0.78 | MMP8 (0.51) | KMT2AMMP8LMNASMN1; SMN2PIN1 | |
| SCHEMBL1646940 | 0.78 | MMP8 (0.51) | KMT2AMMP8LMNASMN1; SMN2PIN1 | |
| SCHEMBL28497599 | 0.77 | MMP8 (0.54) | KMT2AMMP8SMN1; SMN2PIN1MEN1 | |
| SCHEMBL1661290 | 0.77 | MMP8 (0.54) | KMT2AMMP8SMN1; SMN2PIN1MEN1 | |
| SCHEMBL21555695 | 0.76 | MMP8 (0.53) | KMT2AMMP8SMN1; SMN2PIN1MEN1 | |
| SCHEMBL25600199 | 0.76 | MMP8 (0.53) | KMT2AMMP8SMN1; SMN2PIN1MEN1 | |
| SCHEMBL28258997 | 0.76 | MMP8 (0.53) | KMT2AMMP8SMN1; SMN2PIN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8268949-A | — | — | None | — | — | JP | disclosed |
| JP-H08268949-A | DIPHENYLMETHYLENE DERIVATIVE | EISAI CO LTD | 1996-10-15 | — | — | JP | disclosed |