Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888583 | 0.94 | TSHR (0.43) | MMP8MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL10358539 | 0.91 | MMP8 (0.47) | MMP8MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL29008752 | 0.88 | TSHR (0.39) | MMP8MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL1244565 | 0.85 | MEN1 (0.54) | MMP8MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL5526857 | 0.84 | TSHR (0.39) | MMP8MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL23091475 | 0.83 | MEN1 (0.52) | MMP8MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL27889245 | 0.83 | MEN1 (0.52) | MMP8MEN1KMT2AL3MBTL1TSHR | |
| Ammonia Solution, Strong SCHEMBL29049233 | 0.83 | MEN1 (0.52) | MMP8MEN1KMT2AL3MBTL1TSHR | |
| Iodide SCHEMBL10533617 | 0.83 | MEN1 (0.52) | MMP8MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL9052824 | 0.82 | MMP8 (0.53) | MMP8MEN1KMT2AL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996001806-A1 | GLYCINAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS UTILIZING THE SAME | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1996-01-25 | — | — | WO | disclosed |