Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888583 | 0.94 | TSHR (0.43) | TSHRSMN1; SMN2ALDH1A1MMP8L3MBTL1 | |
| SCHEMBL9052829 | 0.88 | MMP8 (0.43) | TSHRSMN1; SMN2ALDH1A1MMP8L3MBTL1 | |
| SCHEMBL5526857 | 0.84 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1MMP8L3MBTL1 | |
| SCHEMBL28557115 | 0.80 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL809243 | 0.80 | DGAT1 (0.40) | TSHRALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL10358539 | 0.79 | MMP8 (0.47) | TSHRSMN1; SMN2ALDH1A1MMP8L3MBTL1 | |
| SCHEMBL27817463 | 0.79 | TSHR (0.36) | TSHRSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL29008744 | 0.79 | MEN1 (0.48) | TSHRSMN1; SMN2ALDH1A1MMP8L3MBTL1 | |
| SCHEMBL29674742 | 0.78 | DGAT1 (0.39) | TSHRALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28725041 | 0.78 | DGAT1 (0.48) | TSHRSMN1; SMN2ALDH1A1MMP8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912755-B | Catalyst composition for olefin polymerization and application thereof | 张一锴 | 2023-06-02 | — | — | CN | disclosed |