Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154489 | 0.82 | TDP1 (0.46) | TDP1FFAR1MAOAMAOBKEAP1 | |
| SCHEMBL10528704 | 0.82 | FFAR1 (0.47) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2817046 | 0.80 | TDP1 (0.47) | TDP1NPC1RAB9AFFAR1KEAP1 | |
| Phosphonic Acid SCHEMBL3817713 | 0.79 | FFAR1 (0.56) | TDP1FFAR1MAOAMAOBKEAP1 | |
| SCHEMBL7290855 | 0.78 | ALDH1A1 (0.47) | TDP1NPC1RAB9AFFAR1MAOA | |
| SCHEMBL17061044 | 0.77 | LMNA (0.53) | TDP1NPC1RAB9AFFAR1MAOB | |
| SCHEMBL9052475 | 0.77 | FFAR1 (0.42) | TDP1FFAR1MAOAMAOBKEAP1 | |
| SCHEMBL9189061 | 0.76 | — | — | |
| SCHEMBL7434838 | 0.76 | FFAR1 (0.49) | FFAR1MAOAMAOBSMN1; SMN2NOS1 | |
| SCHEMBL698616 | 0.75 | TSHR (0.48) | TDP1NPC1RAB9AKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996000733-A1 | DIPHOSPHATE OR TRIPHOSPHATE NON-HYDROLYSABLE STABLE ANALOGUES AND METHODS FOR THEIR PREPARATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1996-01-11 | — | — | WO | disclosed |