SCHEMBL9052957

SCHEMBL9052957

CC(C)(C)COC(=O)N1CCC(OS(C)(=O)=O)C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 5/20 0.41
PIK3CD O00329 1/20 0.39
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35
JAK1 P23458 3/20 0.35
JAK2 O60674 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
HTT P42858 1/20 0.35
GAA P10253 2/20 0.34
MMP13 P45452 1/20 0.34
TSHR P16473 1/20 0.34
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
THRB P10828 1/20 0.32
ATM Q13315 1/20 0.32
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23585416 0.85 GAA (0.47) L3MBTL1HTTGAATSHRTP53
SCHEMBL26704154 0.82 PIK3CD (0.41) GPR119PIK3CDJAK1JAK2L3MBTL1
SCHEMBL66145 0.81 GPR119 (0.48) GPR119PIK3CDMAPTALDH1A1SMN1; SMN2
SCHEMBL66134 0.81 GPR119 (0.48) GPR119PIK3CDMAPTALDH1A1SMN1; SMN2
SCHEMBL330785 0.81 GPR119 (0.48) GPR119PIK3CDMAPTALDH1A1SMN1; SMN2
SCHEMBL31131213 0.80 SMN1; SMN2 (0.47) GPR119PIK3CDL3MBTL1HTTGAA
SCHEMBL13978434 0.80 F10 (0.42) GPR119L3MBTL1HTTGAATSHR
SCHEMBL31682843 0.80 F10 (0.42) GPR119L3MBTL1HTTGAATSHR
SCHEMBL2360585 0.80 SMN1; SMN2 (0.47) GPR119PIK3CDL3MBTL1HTTGAA
SCHEMBL7540588 0.80 F10 (0.42) GPR119L3MBTL1HTTGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996008968-A1 INSECT CONTROL WITH SUBSTITUTED TRIAZOLE AND TETRAZOLE COMPOUNDS DOWELANCO (US) 1996-03-28 WO disclosed
US-5393767-A Insect control with substituted triazole and tetrazole compounds DOWELANCO (US) 1995-02-28 US disclosed