Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | F13A1 | P00488 | 2/20 | 0.33 |
| ▸ | TGM2 | P21980 | 2/20 | 0.33 |
| ▸ | TGM1 | P22735 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31682843 | 1.00 | F10 (0.42) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13978434 | 1.00 | F10 (0.42) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6497279 | 0.92 | F10 (0.40) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL31682777 | 0.89 | F10 (0.35) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL23585416 | 0.84 | GAA (0.47) | L3MBTL1HTTGAALMNATSHR | |
| SCHEMBL17235878 | 0.80 | BTK (0.38) | — | |
| SCHEMBL9052957 | 0.80 | GPR119 (0.41) | GPR119L3MBTL1HTTGAALMNA | |
| SCHEMBL2360585 | 0.78 | SMN1; SMN2 (0.47) | GPR119L3MBTL1HTTGAALMNA | |
| SCHEMBL31131213 | 0.78 | SMN1; SMN2 (0.47) | GPR119L3MBTL1HTTGAALMNA | |
| SCHEMBL8865061 | 0.78 | GPR119 (0.38) | F10PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235456-A1 | PENEM ANTIBACTERIALS AGAINST MYCOBACTERIAL PATHOGENS AND D,D- AND L,D TRANSPEPTIDASES | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-12-07 | — | — | WO | disclosed |
| EP-0928787-B1 | Process for the preparation of 3-amino-pyrrolidine derivatives | BASILEA PHARMACEUTICA AG (CH) | 2002-06-05 | — | — | EP | disclosed |
| EP-1138672-A1 | Process for the preparation of 3-amino-pyrrolidine derivatives | Basilea Pharmaceutica AG (CH) | 2001-10-04 | — | — | EP | disclosed |
| US-5977381-A | Process for making 3-amino-pyrolidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0928787-A1 | Process for the preparation of 3-amino-pyrrolidine derivatives | F. Hoffmann-La Roche AG (CH) | 1999-07-14 | — | — | EP | disclosed |