Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.46 |
| ▸ | RARG | P13631 | 10/20 | 0.46 |
| ▸ | RARA | P10276 | 9/20 | 0.46 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054684 | 0.87 | RARB (0.38) | RARBRARGRARAHSPA9RXRA | |
| SCHEMBL7195918 | 0.75 | KDM4E (0.50) | RARBRARGRARAHSPA9TDP1 | |
| SCHEMBL9055225 | 0.74 | RARA (0.38) | RARBRARGRARAHSPA9ALDH1A1 | |
| SCHEMBL9054067 | 0.74 | RARA (0.38) | RARBRARGRARAHSPA9ALDH1A1 | |
| SCHEMBL669879 | 0.74 | RARB (0.59) | RARBRARGRARARXRA | |
| Hydrochloric Acid SCHEMBL21750654 | 0.73 | KDM4E (0.49) | RARBRARGRARAHSPA9TDP1 | |
| SCHEMBL9054411 | 0.73 | RARB (0.48) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL7698960 | 0.73 | RARB (0.57) | RARBRARGRARAHSPA9RXRA | |
| SCHEMBL7191655 | 0.73 | HSPA9 (0.65) | RARBRARGRARAHSPA9ALDH1A1 | |
| SCHEMBL3838099 | 0.72 | RARB (0.57) | RARBRARGRARARXRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498755-A | IMINE COMPOUNDS FOR SKIN DISORDERS AND ANTIINFLAMMATORY AGENTS | ALLERGAN, INC. | 1996-03-12 | — | — | US | disclosed |
| WO-1996006070-A1 | DISUBSTITUTED ARYL AND HETEROARYL IMINES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN (US) | 1996-02-29 | — | — | WO | disclosed |