SCHEMBL9052969

SCHEMBL9052969

O=C(O)c1cccc(S(=O)(=O)Oc2cc(C(=O)O)cc(O)c2O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
PTGS2 P35354 1/20 0.47
POLB P06746 1/20 0.45
POLA1 P09884 1/20 0.45
ANTXR2 P58335 1/20 0.45
F2 P00734 3/20 0.44
PRSS1 P07477 3/20 0.44
PRSS2 P07478 3/20 0.44
PRSS3 P35030 3/20 0.44
MAPT P10636 3/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 2/20 0.44
CA12 O43570 2/20 0.44
CA6 P23280 2/20 0.44
CA9 Q16790 2/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.44
CA3 P07451 1/20 0.44
SELL P14151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9054334 0.90 PTGS2 (0.51) CA1CA2PTGS2POLBPOLA1
SCHEMBL9056691 0.88 PTGS2 (0.44) CA1CA2PTGS2POLBPOLA1
SCHEMBL9054965 0.88 PTGS2 (0.48) CA1CA2PTGS2POLBPOLA1
SCHEMBL9056474 0.83 TP53 (0.49) CA1CA2POLBF2PRSS1
SCHEMBL9056482 0.83 TP53 (0.49) CA1CA2POLBF2PRSS1
SCHEMBL7937565 0.80 PTGS2 (0.51) CA1CA2PTGS2POLBPOLA1
SCHEMBL9052978 0.80 PTGS2 (0.47) CA1CA2PTGS2POLBPOLA1
SCHEMBL9053538 0.77 PTGS2 (0.44) CA1CA2PTGS2POLBPOLA1
SCHEMBL9055309 0.77 KMT2A (0.48) CA1CA2PTGS2POLBPOLA1
SCHEMBL9053430 0.75 PTGS2 (0.45) CA1CA2PTGS2POLBPOLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996008483-A1 GALLIC ACID DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS ROUSSEL UCLAF (FR) 1996-03-21 WO disclosed