Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 5/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498775 | 0.90 | AHCY (0.51) | AHCYPRMT5WDR77ADORA2BADORA3 | |
| SCHEMBL9155536 | 0.90 | AHCY (0.51) | AHCYPRMT5WDR77ADORA2BADORA3 | |
| SCHEMBL11884247 | 0.89 | AHCY (0.53) | AHCYPRMT5WDR77ADORA2BADORA3 | |
| SCHEMBL11884228 | 0.89 | AHCY (0.53) | AHCYPRMT5WDR77ADORA2BADORA3 | |
| SCHEMBL23478169 | 0.88 | NT5E (0.49) | AHCYPRMT5WDR77ADORA2BADORA3 | |
| SCHEMBL30950419 | 0.88 | PRMT5 (0.48) | AHCYPRMT5WDR77ADORA2BADORA3 | |
| SCHEMBL29379600 | 0.88 | NT5E (0.49) | AHCYPRMT5WDR77ADORA2BADORA3 | |
| SCHEMBL29361839 | 0.88 | NT5E (0.49) | AHCYPRMT5WDR77ADORA2BADORA3 | |
| SCHEMBL4830646 | 0.88 | PRMT5 (0.51) | AHCYPRMT5WDR77ADORA2BADORA3 | |
| SCHEMBL10365540 | 0.87 | PRMT5 (0.58) | AHCYPRMT5WDR77ADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996000585-A1 | DIPHOSPHATE OR TRIPHOSPHATE ANALOGUE CONJUGATES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1996-01-11 | — | — | WO | disclosed |