Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | AHCY | P23526 | 4/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | TYMP | P19971 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052971 | 0.88 | AHCY (0.49) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL10912591 | 0.84 | PRMT5 (0.54) | PRMT5WDR77PDE4APDE4BPDE4C | |
| SCHEMBL3852963 | 0.80 | PDE4D (0.49) | PRMT5WDR77PDE4APDE4BPDE4C | |
| Acetone SCHEMBL5504139 | 0.79 | SLC29A1 (0.66) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL6671390 | 0.77 | ADORA3 (0.67) | PDE4APDE4BPDE4CPDE4DAHCY | |
| SCHEMBL9155536 | 0.77 | AHCY (0.51) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL5498775 | 0.77 | AHCY (0.51) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL6897952 | 0.77 | ADORA2A (0.51) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL4520798 | 0.76 | AHCY (0.68) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL2117335 | 0.76 | AHCY (0.68) | PRMT5WDR77AHCYADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345164-B2 | Production method of 5′-acyloxynucleoside compound | AJINOMOTO CO., INC. (JP) | 2008-03-18 | — | — | US | claimed |
| US-20040230053-A1 | Production method of 5'-acyloxynucleoside compound | AJINOMOTO CO., INC. (JP) | 2004-11-18 | — | — | US | claimed |
| EP-1471071-A1 | Production method of 5'-acyloxynucleoside compound | Ajinmoto Co., Inc. (JP) | 2004-10-27 | — | — | EP | claimed |
| US-7345164-B2 | Production method of 5′-acyloxynucleoside compound | AJINOMOTO CO., INC. (JP) | 2008-03-18 | — | — | US | disclosed |
| US-20040230053-A1 | Production method of 5'-acyloxynucleoside compound | AJINOMOTO CO., INC. (JP) | 2004-11-18 | — | — | US | disclosed |
| EP-1471071-A1 | Production method of 5'-acyloxynucleoside compound | Ajinmoto Co., Inc. (JP) | 2004-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040230053-A1 | Production method of 5'-acyloxynucleoside compound | ALKBH2, DUT, ALKBH1 | PRMT5 842/4885WDR77 1657/4885PDE4A 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.