SCHEMBL9052995

SCHEMBL9052995

C=CCc1ncnc(C2CCNCC2)n1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.33
CHRM4 P08173 1/20 0.32
USP7 Q93009 1/20 0.31
HRH4 Q9H3N8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5485611 0.72 CDC7 (0.30)
SCHEMBL28170122 0.70 HRH4 (0.46) HRH3CHRM4USP7HRH4
Hydrochloric Acid SCHEMBL28169529 0.69 HRH4 (0.45) HRH3CHRM4USP7HRH4
SCHEMBL3783902 0.67 HRH3 (0.44) HRH3CHRM4USP7HRH4
SCHEMBL1251832 0.64 ALDH1A1 (0.35)
SCHEMBL1703128 0.64
SCHEMBL7590048 0.64 ADORA2A (0.36)
SCHEMBL24067526 0.63 SLC18A3 (0.42) HRH3USP7HRH4
SCHEMBL9004431 0.62 SLC18A3 (0.50)
SCHEMBL28460425 0.61 HRH4 (0.40) HRH3HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0345220-B1 Polyamines partially substituted by bis-piperidyl-triazines CIBA GEIGY AG (CH) 1996-08-28 EP disclosed
EP-0345221-B1 Polyamines partially substituted by piperidine-triazines CIBA GEIGY AG (CH) 1995-12-27 EP disclosed
US-4933451-A LIGHT, HEAT AND OXIDATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1990-06-12 US disclosed
US-4927930-A LIGHT, HEAT AND OXIDATION STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1990-05-22 US disclosed
EP-0345221-A2 Polyamines partially substituted by piperidine-triazines CIBA-GEIGY AG (CH) 1989-12-06 EP disclosed
EP-0345220-A2 Polyamines partially substituted by bis-piperidyl-triazines CIBA-GEIGY AG (CH) 1989-12-06 EP disclosed