Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | QDPR | P09417 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418044 | 0.83 | — | — | |
| SCHEMBL615556 | 0.79 | SLC18A3 (0.46) | HRH3SLC18A3SIGMAR1HTR2C | |
| SCHEMBL3188650 | 0.78 | CYP11B2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL18952739 | 0.77 | HTR2C (0.47) | HRH3SLC18A3SIGMAR1HTR2C | |
| SCHEMBL3214949 | 0.76 | CYP11B2 (0.42) | — | |
| SCHEMBL3185400 | 0.76 | CYP11B2 (0.42) | — | |
| SCHEMBL31736812 | 0.76 | SLC18A3 (0.48) | HRH3SLC18A3SIGMAR1USP7HRH4 | |
| SCHEMBL25330171 | 0.74 | USP7 (0.46) | HRH3SLC18A3SIGMAR1USP7HRH4 | |
| SCHEMBL12068365 | 0.74 | HTR2C (0.43) | HRH3SLC18A3SIGMAR1USP7HTR2C | |
| SCHEMBL14734253 | 0.74 | HTR3A (0.41) | HRH3SLC18A3SIGMAR1USP7HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101772537-B | Flame-proofed polymer material | CHEM FAB BUDENHEIM KG | 2013-07-10 | — | — | CN | claimed |
| CN-101772537-A | Flame-proofed polymer material | CHEM FAB BUDENHEIM KG | 2010-07-07 | — | — | CN | claimed |
| US-7855194-B2 | Pyrimidine, quinazoline, pteridine and triazine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2010-12-21 | — | — | US | disclosed |
| US-20070225271-A1 | Pyrimidine, quinazoline, pteridine and triazine derivatives | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225271-A1 | Pyrimidine, quinazoline, pteridine and triazine derivatives | SSTR5, SSTR3, SSTR1 | HRH3 225/4885SLC18A3 948/4885SIGMAR1 613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.