Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752438 | 0.80 | CHRNB2 (0.40) | — | |
| SCHEMBL7787553 | 0.77 | KMT2A (0.34) | — | |
| SCHEMBL717078 | 0.77 | — | — | |
| SCHEMBL5661852 | 0.76 | CHRNB2 (0.44) | — | |
| SCHEMBL3914034 | 0.76 | — | — | |
| SCHEMBL715395 | 0.74 | — | — | |
| SCHEMBL7786231 | 0.73 | CHRNB2 (0.47) | ALDH1A1 | |
| SCHEMBL4984 | 0.73 | CHRNB2 (0.40) | — | |
| SCHEMBL3544740 | 0.72 | — | — | |
| SCHEMBL854160 | 0.72 | MAPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696277-A1 | HIV PROTEASE INHIBITORS USEFUL FOR THE TREATMENT OF AIDS | MERCK & CO. INC. (US) | 1996-02-14 | — | — | EP | disclosed |