Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786231 | 0.88 | CHRNB2 (0.47) | KMT2ACHRNB2CHRNA4CHRNA7CHRNB4 | |
| SCHEMBL752438 | 0.81 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL7784038 | 0.80 | KMT2A (0.46) | KMT2A | |
| SCHEMBL844879 | 0.78 | CHRNB2 (0.32) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL9053082 | 0.77 | L3MBTL1 (0.36) | — | |
| SCHEMBL5661852 | 0.77 | CHRNB2 (0.44) | KMT2ACHRNB2CHRNA4CHRNA7CHRNB4 | |
| SCHEMBL2250070 | 0.75 | HSD17B10 (0.33) | — | |
| SCHEMBL715395 | 0.75 | — | — | |
| SCHEMBL844181 | 0.75 | — | — | |
| SCHEMBL4984 | 0.74 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823420-B1 | Substituted vinylurea derivatives and their use as ACAT inhibitors | SS PHARMACEUTICAL CO (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5866609-A | PROPHYLACTIC AND THERAPEUTIC AGENTS FOR ARTERIOSCLEROSIS. | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0823420-A2 | Substituted vinylurea derivatives and their use as ACAT inhibitors | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |