Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493113 | 0.76 | MAPT (0.41) | MAPTTDP1L3MBTL1TSHRPOLB | |
| SCHEMBL1537422 | 0.74 | MAPT (0.40) | MAPTTDP1L3MBTL1TSHRPOLB | |
| SCHEMBL7416756 | 0.74 | SMN1; SMN2 (0.51) | MAPTTDP1RECQLL3MBTL1POLB | |
| SCHEMBL1043878 | 0.73 | ATM (0.50) | MAPTBLMTDP1RECQLL3MBTL1 | |
| SCHEMBL9799560 | 0.73 | TSHR (0.63) | MAPTTDP1L3MBTL1TSHRPOLB | |
| SCHEMBL535991 | 0.73 | MAOA (0.47) | MAPTTDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL2026026 | 0.73 | TSHR (0.63) | MAPTTDP1L3MBTL1TSHRPOLB | |
| SCHEMBL1774826 | 0.71 | ATM (0.43) | MAPTTDP1L3MBTL1TSHRPOLB | |
| SCHEMBL4827392 | 0.71 | HDAC1 (0.38) | MAPTTDP1L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL1043478 | 0.70 | CES2 (0.52) | MAPTBLMTDP1RECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715618-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | disclosed |