Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 5/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | DVL1 | O14640 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053281 | 1.00 | HTR2C (0.38) | HTR2CHTR2AHTR2BDGAT1FFAR4 | |
| SCHEMBL9056435 | 0.86 | HPGDS (0.41) | HTR2CHTR2BDGAT1FFAR4HPGDS | |
| SCHEMBL9056444 | 0.86 | HPGDS (0.41) | HTR2CHTR2BDGAT1FFAR4HPGDS | |
| Hydrochloric Acid SCHEMBL9057145 | 0.86 | HPGDS (0.40) | HTR2CHTR2BDGAT1FFAR4HPGDS | |
| SCHEMBL9054835 | 0.84 | SMN1; SMN2 (0.38) | DGAT1FFAR4ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9054839 | 0.84 | SMN1; SMN2 (0.38) | DGAT1FFAR4ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9057543 | 0.77 | FFAR4 (0.38) | DGAT1FFAR4ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9057548 | 0.77 | FFAR4 (0.38) | DGAT1FFAR4ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9055358 | 0.77 | HPGDS (0.36) | DGAT1FFAR4HPGDSBAZ2A | |
| SCHEMBL9055350 | 0.77 | HPGDS (0.36) | DGAT1FFAR4HPGDSBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | disclosed |